Adjacent Segment Degeneration and Adjacent Segment Disease: Implications following Spinal Fusion Surgery
Mehran Ekrami1, Mohsen Khamoushi1, Samin Safarian2, Alireza Davoudi2, Amirmohammad Soleimanian2, Asef Yoonesi3, Daniel Kheradmand1, Neda Kamandi2*, Melika Payrovedin3, Seyed Ali Shariat Razavi1, Masoumeh Taghdisi4, Amirhossein Beheshtdoost5, Mohammad Reza Boustani5 and Nima Nabavi6
1 Department of Neurosurgery, Mashhad University of Medical Sciences, Mashhad, Iran.
2 Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
3 Faculty of Medicine, North Khorasan University of Medical Sciences, Bojnourd, Iran.
4 Student Research Committee, Islamic Azad University, Mashhad Branch, Mashhad, Iran.
5 Faculty of Medicine, AJA University of Medical Sciences, Tehran, Iran.
6 Nuclear Medicine Research Centre, Mashhad University of Medical Sciences, Mashhad, Iran.
*Corresponding Author: Neda Kamandi, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
DOI: https://doi.org/10.58624/SVOANE.2024.05.0130
Received: January 29, 2024 Published: March 06, 2024
Abstract
Spinal fusion is a common and effective option for patients with symptomatic degenerative disc disorders. However, concerns have raised over the probability of adjacent segment degeneration (ASDe) and adjacent segment disease (ASDi) following spinal instrumentation. Current study sought to document evidence on the incidence of ASDe and ASDi after lumbar fusion surgery and the risk factors precipitating adjacent pathologies. Given the benefits of spinal fusion surgery, it remains unclear whether adjacent pathologies are attributed to the natural degeneration or the adjacent fusion.
Keywords: Adjacent segment degeneration, Adjacent segment disease, Spinal fusion surgery, Lumbar spine
Citation: Ekrami M, Khamoushi M, Safarian S, Davoudi A, Soleimanian A, Yoonesi A, Kheradmand D, Kamandi N, Payrovedin M, Razavi SAS, Taghdisi M, Beheshtdoost A, Boustani MR, Nabavi N. Adjacent Segment Degeneration and Adjacent Segment Disease: Implications following Spinal Fusion Surgery. SVOA Neurology 2024, 5:2, 68-72.
