Neurological Manifestations of Hyperosmolar Hyperglycemic State: A Case Report and A Review of the Literature
Panagiotis Gklinos*
The Royal London Hospital, Whitechapel Rd, London E1 1FR, United Kingdom.
*Corresponding Author: Panagiotis Gklinos, The Royal London Hospital, Whitechapel Rd, London E1 1FR, United Kingdom.
DOI: https://doi.org/10.58624/SVOANE.2023.04.084
Received: March 01, 2023 Published: March 10, 2023
Abstract
Hyperosmolar hyperglycemic state (HHS), a life-threatening complication of diabetes mellitus, may initially manifest with a broad spectrum of neurological symptoms. These include encephalopathy, coma, chorea-hemiballismus and epileptic activity. Focal motor seizures are among the most common manifestations whilst aphasia has rarely been described so far. Based on a recent experience from our hospital, we herein report a rare case of a patient with non-ketotic hyperglycemia-induced global aphasia, followed by focal motor seizures and attempt a comprehensive review of the literature with regards to the various neurological syndromes through which, undiagnosed diabetes and HHS may present. Neurological aspects of HHS are not so well-documented and are certainly under-represented in the literature.
Keywords: epilepsy, global aphasia, focal seizures, hyperglycemia, diabetes mellitus, hemichorea-hemiballismus, coma
Citation: Gklinos P. Neurological Manifestations of Hyperosmolar Hyperglycemic State: A Case Report and A Review of the Literature. SVOA Neurology 2023, 4:2, 13-19
