Schizencephaly Diagnosed After Childhood: Report of Two Cases



César Marcelo Hinojosa Cavada, MD1*, Fernanda Flores Alfaro, MD1, Carlos Alberto Soto Rincón, MD1, Rómulo Ramírez Gutiérrez, MD1 and Claudia Victoria Torres González, MD1

1Department of Neurology, Universidad Autónoma de Nuevo León, Mexico.

*Corresponding Author: Dr. Fernanda Flores Alfaro, MD, Department of Neurology, Universidad Autónoma de Nuevo León, Mexico.

Received: August 03, 2022     Published: August 26, 2022

 

Abstract

Schizencephaly is a rare congenital malformation of the brain in which there are abnormal clefts lined by cortical gray matter that allow communication between the subpial space and the lateral ventricle in the cerebral hemispheres, as a result of a neuronal migration disorder. Due to its rarity, the study of this condition has been limited, and knowledge about its etiology, diagnosis, management, and prognosis is still unclear, with the vast majority of published studies occurring in pediatric patients. We present two cases, one is a 32-year-old man and the other is a 17-year-old woman who attended our unit, in both cases the diagnosis of schizencephaly was established. Since most of what is known about schizencephaly has been reported in children; Through this case report, we intend to offer our experience in the evaluation, diagnosis, and management of this rare condition in adults.

Keywords: seizures, electroencephalogram, brain, epilepsy, schizencephaly, antiepileptic

Citation: Cavada CMH, Alfaro FF, Rincon CAS, Gutierrez RR, Gonzalez CVT. “Schizencephaly Diagnosed After Childhood: Report of Two Cases”. SVOA Neurology 2022, 3:4, 165-167.