Advances in Genomics and Bioinformatics Methods for Analyzing Gene Expression in Staphylococcus Aureus Associated with Atopic Dermatitis
Yashoda Pariyar*
Yashoda Pariyar, MSc Microbiology with advanced practice, Teesside University, UK.
*Corresponding Author: Yashoda Pariyar, MSc Microbiology with advanced practice, Teesside University, UK.
https://doi.org/10.58624/SVOAMB.2025.06.004
Received: July 24, 2024
Published: January 30, 2025
Citation: Pariyar Y. Advances in Genomics and Bioinformatics Methods for Analyzing Gene Expression in Staphylococcus Aureus Associated with Atopic Dermatitis. SVOA Microbiology 2025, 6:1, 25-34. doi:10.58624/SVOAMB.2025.06.004
Abstract
This comprehensive review explores the latest advancements in genomics and bioinformatics methods for studying how Staphylococcus aureus behaves in Atopic Dermatitis (AD). It focuses on crucial aspects to understand how this bacterium acts in AD. Firstly, it examines how genes in S. aureus are controlled and how they affect AD. It also looks at the less explored area of how S. aureus' genes are influenced by factors beyond their DNA sequence. The review also investigates how S. aureus settles on the skin in AD and how it manages to stay there. This sheds light on possible ways to intervene and stop its presence. Additionally, it tackles the problem of S. aureus becoming resistant to drugs used to treat AD related infections. It mines into the reasons behind this resistance and how it impacts potential treatments. Moreover, the review emphasizes the crucial role of computer-based tools in studying S. aureus' genes. It evaluates different methods used to understand the complex genetic information linked to AD related S. aureus. By combining different areas like genetics, how the bacterium lives on the skin, drug resistance, and the tools scientists use, this review offers a complete understanding of S. aureus in AD.
Keywords: Staphylococcus aureus, Atopic dermatitis, Gene expression, Epigenetics
