Pathogenesis and Oral-Related Factors in Post-COVID-19 Mucormycosis Patients: A Protocol for a Systematic Review of Case Reports
Guillermo Cano-Verdugo1*, Myriam Angélica De la Garza-Ramos1, Yinli Liu2, Georgina Mayela Núñez-Rocha3, María Natividad Ávila-Ortíz3 and Karina Janett Hernández-Ruiz3
1 Universidad Autónoma de Nuevo León, Facultad de Odontología. Calle Dr. Eduardo Aguirre Pequeño y Silao, Col. Mitras Centro, CP. 64460, Monterrey, Nuevo León, México.
2 Academic Center for Dentistry Amsterdam (ACTA). Department of Orthodontics, Gustav Mahlerlaan 3004, 1081 LA Amsterdam, Netherlands.
3 Universidad Autónoma de Nuevo León, Facultad de Salud Pública y Nutrición. Calle Dr. Eduardo Aguirre Pequeño No. 905, Col. Mitras Centro, CP. 64460, Monterrey, Nuevo León, México.
*Corresponding Author: Guillermo Cano-Verdugo. E-mail: cavgod0002@uanl.edu.mx. Universidad Autónoma de Nuevo León, Facultad de Odontología. Telephone: +52 81 8329-4000, ext. 3164. Calle Dr. Eduardo Aguirre Pequeño y Silao S/N, Col. Mitras Centro, CP. 64460, Monterrey, Nuevo León, México.
DOI: https://doi.org/10.58624/SVOADE.2024.05.0178
Received: May 28, 2024 Published: July 05, 2024
Abstract
During the COVID-19 pandemic, there was a notable increase in cases of oral mucormycosis, with some researchers linking corticosteroid treatment to immune suppression, potentially increasing susceptibility to this fungal infection. Early oral manifestations may serve as indicators for timely diagnosis. This protocol for a systematic review aims to elucidate the pathogenesis and related factors of post-COVID-19 mucormycosis through the analysis of case reports. We will conduct a comprehensive search of relevant articles, excluding review articles and case series. Bias risk will be assessed using the ROBINS-E tool, and certainty of evidence will be evaluated using the GRADE framework. A narrative synthesis of the data will be performed, focusing on sociodemographic profiles, medical and family histories, diagnostic methods, treatment approaches, and dental relevance.
Keywords: Oral mucormycosis, COVID-19, Corticosteroids, Pathogenesis, Case reports.
Citation: Cano-Verdugo G, De la Garza-Ramos MA, Liu Y, Nunez-Rocha GM, Avila-Ortí z MN, Hernandez-Ruiz KJ. Pathogenesis and Oral-Related Factors in Post-COVID-19 Mucormycosis Patients: A Protocol for a Systematic Review of Case Reports. SVOA Dentistry 2024, 5:4, 104-108. doi:10.58624/SVOADE.2024.05.0178
