Host Modulation Therapy: A Mini Review



Periodontal diseases are responsible for tissue destruction which acts as a supporter for dentition. These diseases are initiated by gram negative bacteria which forms biofilm and elicits host inflammatory responses. Mechanical debridement along with various pharmacology agents such as Nonsteroidal anti-inflammatory drugs, Doxycycline, aids in managing periodontitis. Host Modulatory Therapy is a treatment concept that focuses on the reduction of tissue destruction and stabilizing or regenerating the periodontium by modifying or decreasing the regulating destructive aspects of the host response and upregulating protective or regenerated responses. This manuscript reviews the Host Modulatory Therapy that acts as an effective tool adjunct to mechanical therapy in treating periodontal diseases.

Keywords: Biofilms, Nonsteroidal anti-inflammatory drugs, Doxycycline, Host Modulatory Therapy, Regenerated responses.

Citation: Akila Shree Kanagaraj and Vivek Manish kumar Patel. “Host Modulation Therapy: A Mini Review”. SVOA Dentistry 2:1(2021) pages 48-55.