Chronic Lymphocytic Inflammation with Pontine Perivascular Enhancement Responsive to Steroids (CLIPPERS) Mimicking Posterior Circulation Infarction
Aqeel Alameer1, Avinash Kanodia1*, Riccardo Zannoni1, Vilte Balcaityte1 and Jonathan O'Riordan2
1 Department of Radiology, Ninewells Hospital, Dundee, United Kingdom.
2 Department of Neurology, Ninewells Hospital, Dundee, United Kingdom.
*Corresponding Author: Avinash Kanodia, MD, DM, FRCR, Radiology, Ninewells Hospital, Dundee, UK.
DOI: https://doi.org/10.58624/SVOANE.2024.05.0136
Received: April 14, 2024 Published: May 02, 2024
Abstract
CLIPPERS is a rare inflammatory condition of the central nervous system. It is pathologically characterised by white matter perivascular lymphohistiocytic infiltrate with or without parenchymal extension. A male patient in mid sixties presented with dysarthria and facial numbness underwent an MRI brain which supported a diagnosis of a subacute posterior circulation infarct. The patient re-presented with worsening of symptoms and a repeat MRI revealed changes atypical for ischaemia and consistent with CLIPPERS. Our case represents a common presentation of a very rare condition.
Keywords: CLIPPERS, Chronic Lymphocytic Inflammation; Pontine Perivascular Enhancement.
Citation: Alameer A, Kanodia A, Zannoni R, Balcaityte V, O'Riordan J. Chronic Lymphocytic Inflammation with Pontine Perivascular Enhancement Responsive to Steroids (CLIPPERS) Mimicking Posterior Circulation Infarction. SVOA Neurology 2024, 5:3, 104-107.
