Acute Onset of Creutzfeldt-Jakob Disease Resembling Stroke in Absence of Diagnostic EEG Findings
Erika Juliani, MD1* and Matthew Calestino, MD2
1 Neurologist in Orlando, Florida, USA.
2 Internal Medicine Specialists at HCA Florida North Florida Hospital, USA.
*Corresponding Author: Erika Juliani, MD, Neurologist in Orlando, Florida, USA.
DOI: https://doi.org/10.58624/SVOANE.2023.04.0115
Received: November 21, 2023 Published: December 08, 2023
Abstract
We report a case of Creutzfeldt-Jakob disease with acute onset of symptoms with EEG negative for PSWC, resembling a cerebrovascular accident. The patient was diagnosed with sporadic CJD by positive RT-QUIC, positive 14-3-3 protein, T-Tau protein of 14560 pg/mL, brain magnetic resonance imaging (MRI) demonstrating restricted diffusion on DWI in bilateral frontal, temporal, occipital cortex, caudate and putaminal nuclei, as well as T2 FLAIR hyperintensities in the bilateral cerebral cortex and basal ganglia. The entire course of the disease from onset to death was 52 days.
Keywords: CJD, Acute onset, EEG, Myoclonus, Ataxia, Caudate nucleus, Ribboning
Citation: Juliani E, Calestino M. Acute Onset of Creutzfeldt-Jakob Disease Resembling Stroke in Absence of Diagnostic EEG Findings. SVOA Neurology 2023, 4:6, 212-215.