A 66-Year-Old Woman Presented with Sudden Onset Eye Pain and Loss of Vision: Do Not Miss MOGAD



Tarek Matar1*, Mamoun Saeed2, Eleanor Taylor3, Olga Kirmi4 and Fatima Jaffer5

1 Senior clinical fellow in acute medicine, Royal Free hospital Foundation Trust, United Kingdom.

2 Specialist Registrar in Neurology, Imperial collage healthcare NHS trust, United Kingdom.

3 Specialist Registrar in Neuroradiology, Imperial collage healthcare NHS trust, United Kingdom.

4 Consultant Neuroradiologist, Imperial collage healthcare NHS trust, United Kingdom.

5 Consultant Neurologist, Imperial collage healthcare NHS trust, United Kingdom.

*Corresponding Author: Tarek Matar, MsC Neurology, MRCP UK, Senior clinical fellow in acute internal medicine, Royal Free hospital, Pond Street, London NW3 2QG, United Kingdom.

DOI: https://doi.org/10.58624/SVOANE.2023.04.0119

Received: November 29, 2023     Published: December 19, 2023

 

Abstract

A 66 -year- old woman presented to ED with sudden onset eye pain and unilateral loss of vision. She had considerable vascular risk factors including age, hypertension, diabetes mellitus and hypercholesterolemia. She was referred to neurology service with possible arteritic anterior ischemic optic neuropathy (AION). Given her age, painful visual loss and raised ESR, she was treated with steroids for possible giant cell arteritis (GCA). Because of her psychiatric history and poorly controlled diabetes mellitus, steroids were weaned quickly. 6 months later, she had a similar presentation affecting the other eye. MRI head showed disease progression with positive myelin oligodendrocyte glycoprotein (MOG) antibody in serum. MOG associated disorder (MOG-AD) is a steroid responsive inflammatory demyelinating disease but needs long term immunosuppression plan and monitoring of serum antibody.

Keywords: MOG-AD, Optic neuropathy, Corticosteroid

Citation: Matar T, Saeed M, Taylor E, Kirmi O, Jaffer F. A 66-Year-Old Woman Presented with Sudden Onset Eye Pain and Loss of Vision: Do Not Miss MOGAD. SVOA Neurology 2023, 4:6, 241-245