Antioxidant Activity of the Fixed Oil from the Fruits of Caryocar coriaceum Wittm. (Caryocaraceae)
José Thyálisson da Costa Silva1, Francisca de Fátima Silva de Sousa1, Marcos Aurélio Figueirêdo dos Santos1, Severino Denicio Gonçalves de Sousa2, Flávio Silva Tampelini2, Rebeca Azevedo de Lima Madeira3, Francisca Sâmara Muniz dos Santos1, Rafael de Carvalho Mendes3, Dieferson Leandro de Souza1, Luis Pereira de Morais1, Márcia Jordana Ferreira Macêdo1, Mayumi Kimura4, João Pereira da Silva Junior1, Nadghia Figueiredo Leite Sampaio4, Magaly Lima Mota1, Andreia Matias Fernandes1 and José Weverton Almeida-Bezerra1*
1 Regional University of Cariri, Crato - CE, Brazil.
2 Federal University of Mato Grosso, Cuiabá – MT, Brazil.
3 Faculty of Medicine Estácio IDOMED, Juazeiro do Norte – CE, Brazil.
4 Faculty of Medicine Estácio IDOMED, Iguatu – CE, Brazil.
*Corresponding Author: Prof. Dr. José Weverton Almeida-Bezerra, Department of Biological Chemistry, Regional University of Cariri, 63105-000, Crato, CE, Brazil.
DOI: https://doi.org/10.58624/SVOAMB.2024.05.056
Received: November 05, 2024 Published: December 12, 2024
Abstract
Oxidation is a crucial metabolic process that generates energy in cells but also results in the production of free radicals, leading to oxidative stress and the development of chronic diseases such as cancer and neurodegenerative disorders. Reactive oxygen species (ROS) can cause damage to DNA and cellular molecules, making the production of antioxidants essential to mitigate these effects. Fatty acids, in addition to their structural functions, have antioxidant properties and are recognized for protecting against oxidative stress and inflammation. This study focuses on the fixed oil from the fruits of Caryocar coriaceum Wittm., commonly known as pequi, which is rich in fatty acids such as oleic, linoleic, and palmitic acids. The aim was to evaluate the in vitro antioxidant activity of this oil using the DPPH free radical method. After oil extraction, assays were performed that demonstrated a high antioxidant capacity of the oil, with an IC50 of 75.22 µg/mL, similar to the positive control (ascorbic acid, with an IC50 of 9.77 µg/mL). The results indicate that the fixed oil of C. coriaceum is effective in inhibiting oxidation at significant concentrations, highlighting its antioxidant properties and potential in preventing degenerative diseases. The study suggests incorporating the oil into the diet as a promising strategy to promote health, reinforcing the importance of natural resources in therapeutic approaches. Additionally, further research is recommended to explore its applications in preventive medicine.
Keywords: Pequi; Cerrado; Chapada do Araripe; Fatty acid; Free radicals
Citation: da Costa Silva JT, de Sousa FS, dos Santos MAF, de Sousa SDG, Tampelini FS, de Lima Madeira RA, dos Santos FSM, de Carvalho Mendes R, de Souza DL, de Morais LP, Macêdo MJF, Kimura M, da Silva Junior JP, Sampaio NFL, Mota ML, Fernandes AM, Almeida-Bezerra JW. Antioxidant Activity of the Fixed Oil from the Fruits of Caryocar coriaceum Wittm. (Caryocaraceae). SVOA Microbiology 2024, 5:5, 177-182. doi:10.58624 SVOAMB.2024.05.056
