Total Hip Replacement in Ochronosis: Case Report
Mohammed Abdulal Mohammed Saied Hamad, MD, MRCSEd1* and Ammar Babekir Ali Mohammed, MD1
1 Department of Orthopaedics & Traumatology, Sharg Alneel Hospital, Khartoum, Sudan.
*Corresponding Author: Mohammed Abdulal Mohammed Saied Hamad, MD, MRCSEd, Department of Orthopaedics & Traumatology, Sharg Alneel Hospital, Khartoum, Sudan.
DOI: https://doi.org/10.58624/SVOAMR.2024.02.012
Received: May 30, 2024 Published: June 28, 2024
Abstract
Ochronosis is not usual, it is the musculoskeletal manifestation of Alkaptonuria, a condition of abnormal metabolism of Sulphur containing amino acids which result in homogentisic acid accumulation in connective tissues due to homogentisic acid oxidase enzyme deficiency. The urine colour tends to turn into black due to oxidation in air. This is a middle-aged male in his fifties with left sided non traumatic hip pain, x-rays showed OA left hip. Intra op, we noticed the black deposits over the GT and immediately the diagnosis was clear. Urine sample was taken and left in vitro for 24 hours, the colour changed into black. Urinary homogentisic acid level is diagnostic in suspected cases, here no need to perform the test as the diagnosis was clear intra operatively. Ceramic on poly cementless THR was done. The head was preserved in formalin solution for study purposes.
Keywords: Total Hip Replacement; Ochronosis; Case Report
Citation: Hamad MAMS, Mohammed ABA. Total Hip Replacement in Ochronosis: Case Report. SVOA Medical Research 2024, 2:1, 19-22. doi: 10.58624/SVOAMR.2024.02.012