Applications of Hydrogels in the Treatment of Hepatocellular Carcinoma
Gechun Wang1, Xuqiu Shen2, Kexin Jiang3, Yihan Chai2, Lichan Pan3, Qi Chen4* Zhengze Huang2* and Yuelong Liang2*
1Fudan University Shanghai Medical College, Shanghai, 200030, China.
2Department of General Surgery, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, 310016, China.
3Zhejiang University School of Medicine, Hangzhou, 310058, China.
4Department of General Surgery, Hangzhou Fuyang Hospital of Traditional Chinese Medicine, Hangzhou, 311400, China.
*Corresponding Authors: Yuelong Liang, Department of General Surgery, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, 310016, China; Zhengze Huang, Department of General Surgery, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, 310016, China and Qi Chen, Department of General Surgery, Hangzhou Fuyang Hospital of Traditional Chinese Medicine, Hangzhou, 311400, China.
Received: October 19, 2022 Published: November 04, 2022
Abstract
Hepatocellular carcinoma (HCC) is among the most lethal malignant tumors worldwide. Current treatment options are still limited due to not-selective action and therapy resistance. Hydrogels are water-insoluble, hydrophilic, cross-linked, three-dimensional networks of polymer chains having the ability to swell and absorb water but do not dissolve in it. Hydrogels are highly biocompatible and have properties similar to human tissues that make it suitable to be used in various biomedical applications, including drug delivery and tissue engineering. The role of hydrogels in the therapy of HCC is highly emerging in recent years. In this review, we highlighted important characteristics of hydrogels and the application of hydrogels of pioneering strategies for the treatment of hepatocellular carcinoma is also discussed.
Keywords: Hepatocellular carcinoma, Hydrogels, Tumor therapy, Drug delivery system
Citation: Wang G, Shen X, Jiang K, Chai Y, Pan L, Chen Q, Huang Z, Liang Y. “Applications of Hydrogels in the Treatment of Hepatocellular Carcinoma”. SVOA Materials Science &Technology 2022, 4:1, 10-18.
