Clinical, Radiographic, Biochemical and Histological Findings of Central Giant Cell Granuloma: Report of a Case with 8 Years Follow-Up



Central giant cell granuloma is characterized by benign osteolytic intraosseous lesion producing radiolucent radiographic appearance. The differential diagnosis includes the brown tumor of hyperparathyroidism, a multilocular lesion that can compromise the prognosis of these patients. Surgical removal is the gold standard of treatment. Longitudinal evaluations are needed in the face of possible recurrence, even with surgical removal. The purpose of this article is to present a case of central giant cell granuloma that affected a child patient, in whom surgical treatment was instituted and was followed for 8 years, with no signs of recurrence. Several characteristics of central giant cell granuloma were addressed, besides emphasizing the need to perform systemic laboratory tests on the patient in order to eliminate the possibility of the existence of the brown tumor of hyperparathyroidism.

Keywords: central giant cell granuloma; oral diagnosis; oral pathology; benign non-odontogenic tumors; pediatric dentistry

Citation: Lemos JIDS, Manzano F, Reyes A, Shitsuka C and Pedron IG. “Clinical, Radiographic, Biochemical and Histological Findings of Central Giant Cell Granuloma: Report of a Case with 8 Years Follow-Up”. SVOA Dentistry 2:5 (2021) Pages 180-184.