Central Giant Cell Granuloma in Maxillary: Treatment and Literature Review
Nasi Toso M1, Flores Mancilla M2*, Riquelme Mendoza R3
1Maxillofacial Surgeon, Hospital Dr. Gustavo Fricke, Vin a del Mar, Chile.
2Resident UEA, Hospital Dr. Gustavo Fricke, Vin a del Mar, Chile.
3Resident Maxillofacial Surgery, Hospital Dr. Gustavo Fricke, Vin a del Mar, Chile.
*Corresponding Author: Marí a Jose Flores, Resident UEA, Hospital Dr. Gustavo Fricke, Vin a del Mar, Chile.
https://doi.org/10.58624/SVOADE.2025.06.007
Received: December 11, 2024
Published: February 19, 2025
Citation: Nasi Toso M, Flores Mancilla M, Riquelme Mendoza R. Central Giant Cell Granuloma in Maxillary: Treatment and Literature Review. SVOA Dentistry 2025, 6:1, 45 52. doi: 10.58624/SVOADE.2025.06.007
Abstract
Objective: We report the case of combined surgical-pharmacological treatment with local administration of intralesional corticosteroids (IIC) for the management of aggressive central giant cell granuloma (CGCG-A) in the upper jaw with a 4-year follow up.
Methodology: A 2-stage treatment is planned, surgical curettage and intralesional injections with 20 mg/ml triamcinolone diluted in a 2% lidocaine/epinephrine anesthetic solution of 1:200,000 in a 1:1 ratio. Use 1mL of infiltrate solution for every 1 cm3 of radiolucent lesion area applied every 2 weeks, for 6 weeks.
Discussion: At 6 months, complete clinical remission and decreased tooth mobility were observed. Radiologically, there were signs of bone apposition and a decrease in the volume of the lesion. At 3 years there was corticalization of the maxillary sinus without invasion, well-defined maxillary cortical and hyperdensity of the trabeculate. Clinically tooth mobility was not observed, healthy mucous membranes and normal eruption of teeth in root formation. Four years later no recurrence is noticed.
Conclusion: Combined treatment with local administration of IIC is a conservative alternative for the treatment of CGCG-A and can be considered as a therapeutic option to avoid high morbidity without affecting aesthetic and functionality, loss of teeth, and impair the quality of life of a young patient.
Keywords: Giant cell granuloma, Intralesional injections, Corticosteroid, Triamcinolone acetonide
