Association between Periodontal Disease and Atherosclerotic Cardiovascular Diseases - A Systematic Literature Review



Sueli Aparecida de Sousa1, Mário Cappellette Júnior2, Danilo Lourenço3, Denis Honorato Costa4, Luísa Andrade Valle5, José Ricardo Mariano5, Leopoldo Penteado Nucci5* and Irineu Gregnanin Pedron6

1Undergraduate Student, Universidade Brasil, São Paulo, Brazil

2Professor, Post Graduation Program, Department of Otorhinolaryngology and Head and Neck Surgery, Universidade Federal de São Paulo, São Paulo, Brazil

3Professor, Department of Orthodontics, Universidade Brasil, São Paulo, Brazil

4Professor, Department of Gerodontology, Universidade Brasil, São Paulo, Brazil

5Professor, Department of Periodontology, UNIEURO, Brasília, Brazil

6Professor, Department of Periodontology, Implantology, Stomatology, Integrated Clinic, Laser and Therapeutics, Universidade Brasil, São Paulo, Brazil

*Corresponding Author: Leopoldo Penteado Nucci, Professor, Department of Periodontology, UNIEURO, Brasília, Brazil.

Received: October 06, 2022     Published: October 18, 2022

 

Abstract

The COVID 19 is associated with several worsening of chronic inflammatory, including periodontal and coronary artery disease. Following the COVID-19 pandemic, there are indicators that noncommunicable diseases are increasing in prevalence globally and associated with population aging, sedentary lifestyle and increase consumption of caloric diets. It is currently accepted the hypothesis that both groups of these diseases have several similar etiopathogenic factors, including inflammation route. The aim of this systematic review of randomized clinical trials was to investigate the association between periodontal disease and coronary artery disease. From 1786 studies, 30 studies were selected. There is an association between periodontal disease and coronary artery diseases, especially in individuals diagnosed with stage III and IV periodontitis, regardless of the degree, and ischemic stroke after COVID hospitalization.

Keywords: Periodontal Disease; Cardiovascular Disease; Stroke; Clinical trial; Systematic Review.

Citation: de Sousa SA, Junior MC, Lourenço D, Costa DH, Valle LA, Mariano JR, Nucci LP, Pedron IG. “Association between Periodontal Disease and Atherosclerotic Cardiovascular Diseases - A Systematic Literature Review”. SVOA Dentistry 2022, 3:5, 227-234.