A Review of Literature on the Relationship Between Oral Microbiota and Rheumatoid Arthritis
Periodontal disease (PDD) and rheumatoid arthritis (RMA) share comparative pathophysiological pathways like ongoing aggravation with resorption of the proximal bone in immunologically delicate hosts; However, PDD has a notable bacteriological etiology, and the cause of RMA remains unknown. According to some reports, an infectious agent in a vulnerable host may be the cause of RMA and dental microorganisms, in particular, periodontal bacteria, may be the causative agent of RMA infectious agents (mainly Porphyromonas gingivalis). PDD has been demonstrated to be more normal and extreme in patients with RMA showing a connection between the two illnesses. Antibodies against periodontal microbes have been found, and different examinations have discovered bacterial DNA in the serum and synovial liquid of patients with RMA and researched conceivable transmission courses, the presence of periodontal bacterial DNA. Overall, there is no question that RMA and PDD share comparative neurotic components, and there is generous proof for a connection between the two diseases, however more examination, including exploratory models, is expected to show the copathogenicity of oral microscopic organisms.
Keywords: bacterial DNA, oral bacteria, periodontal disease, rheumatoid arthritis
Citation: Vinayaka AM, Dilip N, Jacob PM. “A Review of Literature on the Relationship Between Oral Microbiota and Rheumatoid Arthritis”. SVOA Dentistry 3:1 (2022) Pages 13-20.
